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Apelin Increases Cardiac Contractility via Protein Kinase Cε- and Extracellular Signal-Regulated Kinase-Dependent Mechanisms

• Ábel Perjés, Réka Skoumal, +6 authors István Szokodi
• PloS one
• 2014

BACKGROUND Apelin, the endogenous ligand for the G protein-coupled apelin receptor, is an important regulator of the cardiovascular homoeostasis. We previously demonstrated that apelin is one of the… (More)

Role of reactive oxygen species in the regulation of cardiac contractility.

• Anna-Maria Kubin, Réka Skoumal, +5 authors István Szokodi
• Journal of molecular and cellular cardiology
• 2011

Increased production of reactive oxygen species (ROS) has been linked to the pathogenesis of contractile dysfunction in heart failure. However, it is unclear whether ROS can regulate physiological… (More)

Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart

• Ábel Perjés, Teemu Kilpiö, +9 authors Risto Kerkelä
• Basic Research in Cardiology
• 2015

The G protein-coupled apelin receptor regulates important processes of the cardiovascular homeostasis, including cardiac development, cardiac contractility, and vascular tone. Most recently, a novel… (More)

[Role of reactive oxygen species in the regulation of cardiac function].

• Iván Gábor Horváth, Bálint Kittka, Ábel Perjés, Heikki Ruskoaho, István Szokodi
• Orvosi hetilap
• 2015

Increased production of reactive oxygen species has been implicated in the pathogenesis of congestive heart failure. However, emerging evidence suggests a role for reactive oxygen species in… (More)

Prolactin-releasing peptide regulates cardiac contractility.

• Attila Kónyi, Réka Skoumal, +9 authors István Szokodi
• Regulatory peptides
• 2010

High levels of specific prolactin-releasing peptide (PrRP) binding sites have been found in the myocardium; however, the functional importance of PrRP in the regulation of cardiac function is… (More)

Neuronostatin, a novel peptide encoded by somatostatin gene, regulates cardiac contractile function and cardiomyocyte survival.

• Laura Vainio, Ábel Perjés, +8 authors Risto Kerkelä
• The Journal of biological chemistry
• 2012

Neuronostatin, a recently discovered peptide encoded by somatostatin gene, is involved in regulation of neuronal function, blood pressure, food intake, and drinking behavior. However, the biological… (More)

p38α regulates SERCA2a function.

• Leena Kaikkonen, Johanna M. Magga, +13 authors Risto Kerkelä
• Journal of molecular and cellular cardiology
• 2014

cAMP-dependent protein kinase (PKA) regulates the L-type calcium channel, the ryanodine receptor, and phospholamban (PLB) thereby increasing inotropy. Cardiac contractility is also regulated by p38… (More)

Physiological regulation of cardiac contractility by endogenous reactive oxygen species.

• Ábel Perjés, Anna Kubin, +5 authors István Szokodi
• Acta physiologica
• 2012

Increased production of reactive oxygen species (ROS) has been linked to the pathogenesis of congestive heart failure. However, emerging evidence suggests the involvement of ROS in the regulation of… (More)

Introducing the National Institute for Sports Medicine in Hungary: a complex sports medical healthcare and screening system

• Judit Laki, Ágnes Soós, Péter Jákó, András Tállay, Ábel Perjés, Anita Megyeriné Szabó
• BMJ open sport & exercise medicine
• 2017

The Hungarian National Institute for Sports Medicine (NISM) was founded in 1952 to provide medical coverage for national teams, screening and periodic health evaluation (PHE) for all Hungarian… (More)

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