• Publications
  • Influence
Liquid chromatographic enantioseparation of beta-blocking agents with (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propyl isothiocyanate as chiral derivatizing agent.
The applicability of (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propyl isothiocyanate [(R,R)-DANI] as a recently developed chiral derivatizing agent for the enantioseparation of a series ofExpand
  • 27
  • 3
Principles of micellar electrokinetic capillary chromatography applied in pharmaceutical analysis.
Since its introduction capillary electrophoresis has shown great potential in areas where electrophoretic techniques have rarely been used before, including here the analysis of pharmaceuticalExpand
  • 35
  • 2
  • PDF
Separation of 1,4-benzodiazepines by micellar elektrokinetic capillary chromatography.
In this work the applicability of micellar elektrokinetic capillary chromatography (MECC) for the determination of benzodiazepines (BZD) has been studied. The applied method was used for theExpand
  • 38
  • 1
Thin layer chromatographic analysis of Beta-lactam antibiotics.
PURPOSE The paper describes some thin layer chromatographic procedures that allow simple and rapid separation and identification of penicillins and cephalosporins from complex mixtures. METHODSExpand
  • 11
  • 1
  • PDF
Role of chemical structure in stereoselective recognition of beta-blockers by cyclodextrins in capillary zone electrophoresis.
Most of the beta-blocking drugs for treating diseases of the cardiovascular system are chiral aryloxy-propanolamine derivatives. Tipically, the S(-) enantiomers are more active than the R(+)Expand
  • 30
Role of chemical structure in stereoselective recognition of beta‐blockers and H1‐antihistamines by human serum transferrin in capillary zone electrophoresis
Studies on chiral resolution of beta‐blocker and H1‐antihistamine drugs by CZE using human serum transferrin are described. The drugs with different structures passed a pseudostationary protein zoneExpand
  • 13
Separation and determination of quinolone antibacterials by capillary electrophoresis.
The migration behavior and separation of 13 quinolone antibacterials were investigated by capillary electrophoresis (CE). In order to predict the electrophoretic mobility, the protonationExpand
  • 7
  • PDF
[Separation of 1,4-benzodiazepine derivates by micellar elektrokinetic capillary chromatography].
Our aim was to develop a capillary electrophoresis method for the separation of 1,4-benzodiazepine derivates. Benzodiazepines are hydrophobic substances, neutral from electrophoretic point of view,Expand
  • 2
Possibilities to Improve Benzylpenicillin and Phenoxymethylpenicillin Stability in Acidic Environment
Background: Benzylpenicillin is water soluble natural penicillin used only by parenteral administration. Fast decomposition in acidic environment is the reason why benzylpenicillin can not be orallyExpand
[High performance liquid chromatographic enantiomer separation of beta-blocking agents with a new isothiocyanate type chiral derivatizing agent].
The applicability of (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propyl isothiocyanate [(R,R)-DANI] as a recently developed chiral derivatizing agent for the enantioseparation of a series ofExpand