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Antineoplastic Agents
Known as:
Drugs, Cancer Chemotherapy
, Cancer Drug
, Antitumor Drugs
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A substance that inhibits the maturation, growth or spread of tumor cells.
National Institutes of Health
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Related topics
Related topics
50 relations
Narrower (49)
1,9-dimethylmethylene blue
1-arabinofuranosylcytosine-5'-stearylphosphate
4-S-cysteaminylphenol
Aldesleukin
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Chemotherapy, Cancer, Regional Perfusion
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Trial of a Paclitaxel-Coated Balloon for Femoropopliteal Artery Disease.
K. Rosenfield
,
M. Jaff
,
+12 authors
D. Scheinert
New England Journal of Medicine
2015
Corpus ID: 5075137
BACKGROUND The treatment of peripheral artery disease with percutaneous transluminal angioplasty is limited by the occurrence of…
Expand
Review
2002
Review
2002
The proteasome: a novel target for cancer chemotherapy
J. Almond
,
G. Cohen
Leukemia
2002
Corpus ID: 24554637
The ubiquitin-proteasome system is an important regulator of cell growth and apoptosis. The potential of specific proteasome…
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Highly Cited
2000
Highly Cited
2000
A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy.
R. Olie
,
A. Paula
,
+5 authors
U. Zangemeister‐Wittke
Cancer Research
2000
Corpus ID: 1302378
Survivin, an inhibitor of apoptosis protein, deserves attention as a selective target for cancer therapy because it lacks…
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Review
1999
Review
1999
Twenty years of p53 research: structural and functional aspects of the p53 protein
P. May
,
E. May
Oncogene
1999
Corpus ID: 29467325
From its modest beginnings in 1979, as a transformation-associated protein, to the discoveries that p53 plays a key role in…
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Review
1999
Review
1999
Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death.
C. Dumontet
,
B. Sikic
Journal of Clinical Oncology
1999
Corpus ID: 7635501
PURPOSE To analyze the available data concerning mechanisms of action of and mechanisms of resistance to the antitubulin agents…
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Review
1996
Review
1996
Good Clinical Research Practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents
J. Viby-Mogensen
,
J. Engbæk
,
+6 authors
D. Østergaard
Acta Anaesthesiologica Scandinavica
1996
Corpus ID: 9281001
Based on an international consensus conference held in Copenhagen in the autumn of 1994, a set of guidelines for Good Clinical…
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Highly Cited
1989
Highly Cited
1989
Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II.
J. Markovits
,
C. Linassier
,
+6 authors
A. Larsen
Cancer Research
1989
Corpus ID: 23581915
Tyrosine phosphorylation plays a crucial role in cell proliferation and cell transformation which suggests that tyrosine kinase…
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Highly Cited
1989
Highly Cited
1989
Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors.
A. Gazit
,
P. Yaish
,
C. Gilon
,
A. Levitzki
Journal of Medicinal Chemistry
1989
Corpus ID: 34690018
A novel class of low molecular weight protein tyrosine kinase inhibitors is described. These compounds constitute a systematic…
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Highly Cited
1984
Highly Cited
1984
Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.
E. Nelson
,
K. M. Tewey
,
Leroy F. Liu
Proceedings of the National Academy of Sciences…
1984
Corpus ID: 26819410
The intercalative acridine derivative 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA), but not its isomer o-AMSA, is a…
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Review
1983
Review
1983
ReviewPure appl. Chem: Rinehart, K. L., et al. Marine natural products as sources of antiviral, antimicrobial, and antineoplastic Agents. 53, 795 (1981). (K. L. Rinehart, University of Illinois…
G. Habermehl
1983
Corpus ID: 82642669
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